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Breast J 25(2):226231

In: Metallothionein IV

Pharmacological modulation of A1AT and PR3 alleviated the severity of NASH in mice

Multiple sequence alignment analyses revealed that GSTO1-1 and GSTO2-2 contain a conserved catalytic cysteine residue and GSH binding sites, while other classes of GSTs have different amino acids in these positions, explaining why only GSTOs show DHAR activity 10,13