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This holds particular promise for: Older adults facing chronic low-grade inflammation Immunocompromised individuals Age-related decline in vaccine efficacy Oncology patients recovering from chemo- or radiotherapy-induced immune depletion In the next section, we turn to the brain by examining Epitalons neuroprotective potential and early findings on cognitive health and neurodegeneration

Cellular model, agonist, agonist concentration, time of exposure, level of OR expression or signaling pathway studied are among the different parameters that could influence OR desensitization as previously reviewed (Connor et al., Definition As indicated above, desensitization is defined as a progressive reduction of signal transduction that occurs more or less rapidly after OR activation depending on the agonist and the signaling pathway

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