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Particularly the pyruvate dehydrogenase kinase isoenzyme-4 gene encodes PDK that converts pyruvate, CoA and oxidized nicotinamide adenine dinucleotide (NAD+) into acetyl-CoA, the reduced form of nicotinamide adenine dinucleotide (NADH) and carbon dioxide

10.1073/pnas.2135113100 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhao X., Moore D

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