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doi: 10.1007/978-3-319-75402-4_2 [DOI] [PubMed] [Google Scholar] 95.Mehrzadi S, Hemati K, Reiter RJ, Hosseinzadeh A

Earlier lactate is considered a by-product of enhanced aerobic glycolysis and accumulated in malignant cells, raising the pH of the tumor microenvironment but a recent investigation by Brandon et al

16 , the serum amino acid metabolism of patients with PD at different stages of progression was compared, and significant differences were found between groups for alanine, arginine, phenylalanine, and threonine, indicating that changes in the metabolism of these amino acids are related to the occurrence and progression of PD