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Indeed, in more extreme cases with very aggressive inflammatory activity, a total reset of the patients immune system by autologous bone marrow transplantation has shown remarkable efficacy at stopping new relapses or MRI lesions and even modestly reversing clinical disability (Rush et al., 2019), though currently this aggressive intervention is recommended only for patients with very active inflammatory disease (Miller et al., 2021)

Nevertheless, the emergence of Artificial Intelligence (AI) seems to be a promising approach to identify new class of molecules presenting senolytic effects

The problem the search results promise to solve is real when illness, age, or environmental load push oxidative stress higher than the body can recycle glutathione, detox capacity falls behind and inflammation climbs

p 60K), Boston Pharmaceutical ( 60K), Boston Pharmaceutical ( 60K), Boston Pharmaceutical ( 0.67), with the MASEF score confirming 8 of these diagnoses, resulting in a concordance rate of 72.7%