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Gene Expression Regulation: Research using gene array analysis has reported that GHK-Cu influences the expression of over 4,000 human genes in cellular models including broad upregulation of tissue repair, antioxidant defence, and anti-inflammatory genes, and downregulation of genes associated with inflammation and oxidative stress making it one of the most extensively gene-profiled small peptides in biomedical research

Thus, insulin resistance leading to elevated portal insulin levels may explain, at least partially, the overlap in individual IGF-I levels between older GH-deficient subjects and GH-sufficient subjects (85, 86)

Acute BPA exposure is reported to inhibit voltage-gated Ca +2 currents but increase K + currents 26

Error bars, P values and statistical tests are reported in the figure captions