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The search was performed in multiple databases, including PubMed, Web of Science, and Embase, and was supplemented by manual searches using Google Scholar to ensure completeness

Using multiplex imaging combined with spatial transcriptomics, we demonstrate that the response to hypoxia is durable for a subset of genes that we term the HM even after the cells are reoxygenated to the physiologic O 2 concentrations of breast tissue

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