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Future investigations should incorporate genetically encoded redox biosensors, high-resolution intravital imaging, and single-cell transcriptomic analyses to map localized redox gradients during tendon degeneration and repair

These may include: Mild redness around the puncture point Temporary swelling due to fluid introduction Tenderness or itching as the tissue responds Minor bruising from the needle piercing small blood vessels These reactions are often temporary and subside on their own

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As such, the CDC has created diagnostic guidelines which include additional criteria to confirm a diagnosis of CFS or ME/CFS