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Pubertal exposure to Microcystin-LR arrests spermatogonia proliferation by inducing DSB and inhibiting SIRT6 dependent DNA repair in vivo and in vitro

First, we assessed protein expression in Be(2)-C cells treated with either MitoQ IC50, DPI IC50, vin IC50 or the double and triple drug combinations, versus control ( Supplementary Figures S3 - S6