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Improved Insulin Sensitivity : Lower oxidative stress may preserve pancreatic -cell function, leading to better insulin secretion and glucose metabolism

Synergistic immunotherapy strategy: Gemcitabine releases damage-associated molecular patterns (damage-associated molecular patterns, DAMPs) such as HMGB1 by inducing immunogenic cell death (immunogenic cell death, ICD), producing a synergistic effect with PD-1 inhibitors (Liu H

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Eydallin G, Montero M, Almagro G, Sesma MT, Viale AM, Muoz FJ, Rahimpour M, Baroja-Fernndez E, Pozueta-Romero J