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Sampling blood and measuring GSH in either red blood cells (RBC) or plasma would seem like an acceptable method of determining glutathione (GSH) status, however, both present unique technical difficulties and are open to artefacts

Furthermore, when leaked into the extracellular microenvironment, the intermediate metabolites of melanogenesis, which are also immunosuppressive, may promote evasion of immune responses by the initially transformed melanocyte precursors and their offspring melanoma cells, increasing the risk of melanomagenesis and melanoma growth [60]

J Clin Invest 123(10):45134524 Huang L, Yan M, Kirschke CP (2010) Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic beta-cells by promoting insulin gene transcription