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The GSH/GPX4 axis plays an essential role in counteracting the production of specific phospholipid hydroperoxides in the presence of catalytically active iron

Both glaucoma and control group patients were treated with oxybuprocaine (brand name Benoxil) eye drops before surgery, making it highly likely that the presence of this metabolite in the aqueous humor samples was due to the eye drops

Molecules of nutritional value with antioxidant properties besides GSH, like selenium, zinc and polyphenols, are important in the immune response against SARS-CoV-2 that occurs primary in the lungs (Prez de la Lastra et al., 2021) in critically ill patients with severe COVID-19 acute respiratory distress syndrome (Notz et al., 2021)

To prevent metal-dependent GSH oxidation, we added 5 mM EDTA or GSH and EDTA to cell suspensions of gshA and gshA oppC (see Figure 6A for a schematic overview)