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In the BRONCUS 45 study, there was no difference in the SGRQ scores between the treatment and control groups after 1-year treatment, and there was no improvement in the quality of life with NAC therapy in the second year

We used R version 3.3.3 to conduct statistical on phenotypic distributions and the lmer4 package to estimate variance components to calculate broad sense heritability ( H 2 )

Zhou B, Zhang JY, Liu XS, Chen HZ, Ai YL, Cheng K, Sun RY, Zhou D, Han J, Wu Q