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Mitochondrial dysfunction has been linked to a reduction in fatty acid -oxidation (FAO) that is due to decreased carnitine palmitoyl transferase-1 (CPT-1) activity and decreased fatty acid clearance, resulting in the pathogenesis of NAFL

Firstly, the properties depend on the contributions of both the gliadins and glutenins, with the glutenin subunits forming large three dimensional networks stabilized by inter-chain disulphide bonds which interact with gliadins, and with other glutenin networks, by non-covalent forces, particularly hydrogen bonds

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