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More to know Key ingredients: 0.3% pure retinol, soybean oil, peptides Fragrance-free: yes Best Serum for Puffiness: IOPE Expert PDRN Caffeine Shot Serum Why it's worth it: You might associate mature skin with being thinner, drier, and less firmbut as circulation slows and lymphatic drainage becomes less efficient, puffiness can also start to sneak in (and stick around a little longer than it used to)

Stop looking at milligrams and start asking: How does this get into my blood

For example, NAMPT expression changes during diseases such as cancer, diabetes, and fatty liver disease 211 , and eNAMPT levels decrease with age 328

Yang et al., 2010