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Antiamyloid therapy for Alzheimers diseaseare we on the right road

Coumarinyl aldehyde as a Michael acceptor type of colorimetric and fluorescent probe for cyanide in water

Additionally, the N-terminal tryptophan is among the more oxidation-prone and light-sensitive residues

Safety and translational challenges are considerable and must drive clinical application: immune stimulation carries theoretical risk as well as known risk of worsening autoimmune phenomena or inflammatory toxicities, particularly in the setting of active immunosuppression (e.g., newly diagnosed with cytotoxic therapy, on high-dose steroids)