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Carcinogenesis in the colon has been linked to pathogenic bacteria, such as Helicobacter, Pseudomonas, and Acinetobacter , a process that can ultimately lead to colorectal cancer

van Loon, A

Here we used such iPSC-derived complex liver organoids to assess the specific impact of ALGS-causing mutations on parenchymal and non-parenchymal liver cells, their role on bile duct formation and survival, and the interactions between signaling pathways suspected to play a role in ALGS pathophysiology

In this study, we did not examine the effects of isosteatic acid on spleen function since the company did not disclose the detailed information of excipients including isostearic acid