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Although expression of peroxiredoxins initially increases with oxidative stress (167, 186), severe and sustained oxidative stress can lead to over-oxidation and inactivation of the enzyme (186, 278)

To date, numerous drugs containing antioxidant-like substances have been investigated to either support or replace standard treatments for vitiligo (Table 1)

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Even in areas where G6PD deficiency is endemic, screening of blood donors is not required