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Conclusion: Following molecular diagnosis, clinicians can implement personalized treatment benefiting patients, as the literature already establishes that most of the individuals with GCK-MODY have good glycemic control with diet alone, without pharmacological treatment, and those with HNF1A mutations respond well to low-dose sulfonylureas

This underscores the need for future research to focus on detailed mechanism analysis, systematically evaluate its bidirectional regulatory effects, and avoid therapeutic risks stemming from a one-sided pursuit of single targets

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There are many studies which demonstrate that quercetin consumption at a tolerable dosage could have beneficial biological effects, including antioxidant, anticancer, and anti-inflammatory effects (Li et al., 2016)