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B.MizunoY.MoriH.HallidayG

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Treatment with SLC6A14 inhibitor, -methyl-DL-tryptophan (-MT), ameliorates inflammation and ferroptosis in mice with experimental colitis, which is mediated by decreasing CCAAT enhancer binding protein (CEBPB) expression [11]

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These structural changes greatly increase the GLP-1 like peptide's half life (t 1/2 = 1 week) compared to endogenous GLP-1 (t 1/2 = 2 minutes)

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doi: 10.1016/j.freeradbiomed.2005.07.010

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