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In response to intra-tumoural hypoxia, cancer cells express hypoxia-inducible factor-1 (HIF-1), which induces the expression of the pro-angiogenic vascular endothelial growth factor (VEGF), MET and HGF

Animal cognition studies: Rats treated with Dihexa show dramatically improved performance on spatial memory tasks, with some studies suggesting effects comparable to reversing years of age-related cognitive decline