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Iron overload can be caused by an increase in dietary iron absorption in hereditary hemochromatosis patients [16] and by multiple blood transfusions in -thalassemia patients

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Almeida AF, Borge GIA, Piskula M, Tudose A, Tudoreanu L, Valentov K, Williamson G, Santos CN (2018) Bioavailability of quercetin in humans with a focus on interindividual variation

Additionally, environmental factors like geography, urbanization, and diet play important roles, among which urbanization shows the strongest correlation with reduced fungal diversity, followed by geographic, dietary, and ethnic factors 12,29