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This notion is supported by previous data showing that in CD4 + T lymphocytes aerobic glycolysis was required for optimal IFN production, whereas in the absence of glucose the glycolytic enzyme glycerinaldehyde-3-phosphate-dehydrogenase (GAPDH) functioned as a repressor of IFN mRNA translation (Chang et al., 2013)

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the GSH group up-regulated 17 differential metabolites and down-regulated 16 differential metabolites relative to the NC group

10.1016/j.freeradbiomed.2004.02.075 89 IydaJ