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[36] [37] In doses higher than intended for medicinal use, the hallucinogenic alteration of consciousness, as well as the delirium in particular, are tied to the compound's activity at the M 1 muscarinic receptor

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21 CFR 211.100(a) FDA cited 21 CFR 211.100(a) for failure to establish adequate written procedures for production and process control most frequently: 38 times across the 94 inspection-based warning letters reviewed