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STAT3 dimers subsequently move to the nucleus and modulate cyclin D1 expression, influencing the G1/S transition in hepatocytes

This effect is linked to the expression of CD36, a cell surface protein known for its roles in lipid metabolism, including fatty acid and lipoprotein uptake, as well as its involvement in innate immunity and inflammation

Minor contributions to drug metabolism have been observed in vitro from CYP1A1, CYP2C8, and CYP2C18, though these enzymes are less relevant in vivo due to their lower hepatic expression compared to CYP3A4 (Shimada et al., 1994)

Isolation and characterization of a novel PHGPx gene in Raphanus sativus