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Disclosure of interest: Nothing to disclose for all authors Poster Session II - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.05 - NEUROINTERVENTION P674 - ESOC25-632 IMPACT OF HEMISPHERE ON EVT FOR LARGE ISCHEMIC CORE LVO PATIENTS Manabu Sihrakawa 1 , Kazutaka Uchida 1 , Fumihiro Sakakibara 1 , Hiroshi Yamagami 2 , Nobuyuki Sakai 3 , Takeshi Morimoro 4 , Shinichi Yoshimura 1 1 Hyogo medical University, Nishinomiya, Japan, 2 University of Tsukuba, Tsukuba, Japan, 3 Shimizu hospital, Kyoto, Japan, 4 Hyogo Medical University, Nishinomiya, Japan Background and Aims: Hemispheric differences may influence stroke outcomes

In mice and rats, three distinct GPx4 isoforms, cytosolic GPx4, mitochondrial GPx4 (mGPx4), and nuclear GPx4 (nGPx4), were identified with different functions