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10.1007/s11882-014-0462-4 142 SheenE.TriadafilopoulosG

Autopsy studies, clinical trial data, and post-marketing surveillance analyses revealed neurological, reproductive, musculoskeletal, thrombotic, and cardiovascular harms

FGF21 is produced primarily in the liver in response to metabolic stress and acts as a systemic regulator of energy balance stimulating fatty acid oxidation, promoting adiponectin secretion, and supporting healthy mitochondrial function in brown adipose tissue.* FGF21 levels are closely correlated with metabolic flexibility the ability of cells to switch efficiently between fuel sources

This refers to a condition of the nerves in the neck becoming irritated, causing a variety of symptoms