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To enhance the accumulation of O 2 and photosensitizers within mitochondria precisely, hexyl 5-aminolevulinate hydrochloride (HAL) and 3-bromopyruvic acid (3BP) were simultaneously encapsulated into microparticles of X-ray irradiated tumor cells (X-MP) to prepareHAL/3BP@X-MP for potent PDT (Figure 5A) (Zuo et al., 2021)

In this study, all sample run orders were randomized

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