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[DOI] [PubMed] [Google Scholar] 193.Itzhaki R.F

At the same time, data available in the literature, do not fully support defect in the IEB as a primary etiologic factor leading to the manifestation of IBD and it is unclear whether increased intestinal permeability is a consequence of the inflammatory process (347, 348) or anticipates and contributes to intestinal inflammation (317)

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It has not been approved by the Food and Drug Administration (FDA) for any clinical use and cannot be legally marketed or sold as a drug, a dietary supplement, or a food product