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This hypothesis gave birth to an entire family of short regulatory peptides (Semax, Selank, Cortexin, Noopept, Epitalon, Cerluten and dozens of others) whose synthesis is documented in Russian pharmacological literature

Regul Toxicol Pharmacol 104:128132 Bitzer ZT, Elias RJ, Vijay-Kumar M, Lambert JD (2016) ()Epigallocatechin3gallate decreases colonic inflammation and permeability in a mouse model of colitis, but reduces macronutrient digestion and exacerbates weight loss

This result provides evidence to improve the efficacy in glioma patients resistant to TMZ (Yang et al., 2020)

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