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In the Diazinon-only group consistent with previous studies (27,28), liver tissue damage, hepatocytes show massive vacuolar degeneration in both the centrilobular and periportal areas, correlated with the observed increase in liver weight, suggesting that pesticide-induced liver injury leads to edema and inflammatory cell infiltration

10.1126/scitranslmed.3003985 55 CoppJ

Sakai D, Mochida J, Yamamoto Y, Nomura T, Okuma M, Nishimura K, et al

Overall, our results showed that auranofin and RSL3 reduce growth and induce tumor regression, respectively, of established chemoresistant HR-NB tumors as single agents