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[12] More recently, though, the following data was submitted: IC 50 (nM) NET 1.7, SERT 11, DAT 65.[ [13] cited in [14] ] The revised IC 50 's would adequately explain the lack of efficacy in treating Parkinson's disease, i.e

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As the dorsal side of the hands of the first patient still showed clear pigmentations (figure 1B), the pigment might not represent the doxycycline itself

Resulta decisiva la relacion dosis-respuesta bifasica: a concentraciones mas altas, de 10^-8 a 10^-7 M, el crecimiento se vio inhibido en lugar de estimulado en estos experimentos