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Polyphyllin VII (PPVII), a pennogenin isolated from the rhizomes of Paris polyphylla, was detected to suppress the growth of gastric cancer by inducing autophagy-mediated ferroptosis [122]

One recent study investigating whole genome expression in patients with fibromyalgia with fatigue found an upregulation of centromere protein K (CENPK) and heat shock protein 90 kDa alpha (cytosolic, class A member 1 (HSP90AA1)) genes in fibromyalgia subjects when compared with age-, gender-, and race-matched healthy controls [50]

doi: 10.3389/fimmu.2019.00303 65

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