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If the FDA accepts the carve-out, the generic can launch before the method-of-use patent expires, generating revenue on the unpatented indications while the brand retains market protection for the patented one

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The interaction of UCB with microglia initially affects defensive processes involved with the expression nuclear factor kappa B (NF-B) and of mitogen-activated protein kinases (MAPKs) as well as enhanced phagocytosis and the subsequent generation of pro-inflammatory cytokines

It is very common in gel-type formulas that also contain an oil-phase as well as in cleansers as it also works with most cleansing agents (unlike a lot of other thickeners)