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Description

doi: 10.7326/0003-4819-139-4-200308190-00008 57 BredtBMHiguera-AlhinoDShadeSBHebertSJMcCuneJMAbramsDI

Methods: In this multinational, double-blind, phase II trial (NCT04771273), 295 people aged 1880 years with biopsy-proven MASH (Non-alcoholic fatty liver disease Activity Score 4), liver fibrosis (stage F1F3) and body mass index 25 kg/m 2 were randomized to once-weekly subcutaneous injections of placebo (PBO) or survodutide 2.4, 4.8 or 6.0 mg (escalated over up to 24 weeks)