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Limitations in Clinical Evidence and Trial Design The current orthopaedic literature on peptides is dominated by animal models, small prospective cohorts, and case series, with very limited RCTs

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Gu L, Okada Y, Clinton SK et al (1998) Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice

Complications of vitamin B12 or folate deficiency anaemia Although it's uncommon, vitamin B12 or folate deficiency (with or without anaemia) can lead to complications, particularly if you have been deficient in vitamin B12 or folate for some time