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Table 2 Therapeutic strategies targeting the microbiotabile acidimmune axis in cancer

The results show that an NO adduct on the sulfhydryl group effectively drives intermolecular disulfide bond formation in TTR, converting native protein into the dsNNTTR species, see Fig

While ROSs play essential roles in cell signaling and homeostasis, their overproduction can lead to oxidative stress, which is implicated in aging, cancer, cardiovascular diseases, and metabolic disorders