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Th2-differentiated cells can migrate out of the draining lymph nodes into the lamina propria and secrete pro-inflammatory cytokines, such as IL-5 and IL-13 to further promote the differentiation of downstream pro-inflammatory effector cells such as eosinophils and basophils

However, we are aware of the limitations of this review, especially the lack of homogeneity in the design of the studies, the small sample size of some of them and, above all, our grouping of the different investigations on the same product, since otherwise it would have been impossible to produce a review article and would have been the subject of a treatise in itself

BioFactors 48 (1), 2255

* Revives skin suppleness