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[15] The redox potential (E GSH ) was calculated using the following equation: Where E (roGFP2) is the standard redox potential of the fluorescent protein (280 mV, at pH 7), [12] R is the gas constant (8.315 J K -1 mol -1 ), T is the temperature (K), and F is the Faraday constant (96485 C mol -1 )

Am J Respir Cell Mol Biol 2016;54:1619

Briefly, the safety profile of TLC-2716 was evaluated in CD-1 mice (Charles River Laboratories) administered orally once daily at 0 (vehicle: 100 mM sodium phosphate puffer, 0.5% polyvinylpyrrolidone (PVP