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Timing of developmental program activation is therefore of critical importance in guiding cell fate trajectory and accompanying metabolic programs

7 The need for newer NSAIDs has led to the understanding that the inhibition of the COX-1 isoform is responsible for the side effects of the conventional NSAIDs and the COX-2 is responsible for the beneficial effects such as the anti-inflammatory effects and analgesia

Thermal proteomic profiling identifies redox regulating proteins as potential LCS3 targets After establishing that the cellular response to LCS3 includes apoptosis and oxidative stress, we sought to identify molecular targets of LCS3 through a proteomics-based approach