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Curr Ther Res Clin Exp 100:100737

doi: 10.1016/0005-2736(76)90160-7 78 ColeSPCBhardwajGGerlachJHMackieJEGrantCEAlmquistKCet al

If you want to learn more about the acid and base chemistry of amino acids, check out this article where we go into great detail on the subject

Also, these nucleotides that are incorporated into the saRNA structure must be compatible with the T7 RNA polymerase and cellular translation machinery, as well as the viral nonstructural genes that are necessary for RNA amplification and subsequent protein expression (Maruggi et al., 2019)