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As of mid-2026, Retatrutide is still in Phase 3 trials, with FDA approval expected late this year or early next

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i , Quantification of nigericin-induced NETs in WT and XKR8-deficient BMNs in the presence of the agonists targeting TRPV2 (CBD, 5 M), TRPC3 (GSK1702934A, 100 M), TRPV4 (GSK1016790A, 100 nM), Piezo1 (Yoda1, 10 M) ( n = 10)