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CE-MS for metabolomics: developments and applications in the period 20182020

Hydrogen Peroxide and the Warburg Effect in the Tumor Stroma: Metabolic Coupling If cancer cells produce and secrete hydrogen peroxide, then this also has important metabolic consequences for the tumor microenvironment

Most recently, a double-blinded, randomized, placebo-controlled phase IIa study in patients with refractory chronic cough with an alkaline hypertonic divalent salt pH 9 aerosol (SC0023) confirmed the treatment efficacy results of the exploratory trial, while further reporting a reduction in daily cough rate for patients with heavy cough (19 coughs h 1 ) exceeding 70% relatively to baseline up to 3 weeks post-treatment (NCT07003347)

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