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Maintaining hormonal balance is vital for multiple body functions

The new 6q27 tumor suppressor disheveled-associated binding antagonist of beta-catenin 2 (DACT2), which is frequently silenced by CpG methylation, sensitizes NPC cells to paclitaxel and 5-FU toxicity through -catenin/ Cdc25c signaling and G2/M arrest

To extend the NO release time and improve the controllability of NO release, various NO donors/precursors have been developed, including RONO 2 , RSNOs, NONOates, and metal NO complexes, which are further loaded into various organic and inorganic biomaterial carriers to create NO delivery systems