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Within the central nervous system, glutamate-induced neurotoxicity is associated with iron dysregulation, and both iron chelators and ferroptosis inhibitors have been demonstrated to alleviate this toxicity (Dixon et al., 2012)

A 2017 study in Clinical, Cosmetic and Investigational Dermatology found that when the participants were supplemented with glutathione, the melanin index began to reduce significantly when compared to the placebo groups

& O'Dowd, K