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doi: 10.1096/fj.201802842RR 38

Compared with the healthy mice, there was a significant increase in the serum levels of MDA, and a significant decrease in the serum levels of SOD and GSH-Px in the mice with cachexia receiving saline

Discontinue if abnormal reactions appear after sun exposure on treated areas

Our findings suggest that irisin activates the SIRT1 signaling pathway, which is not exclusive to dopaminergic neurons and may also modulate glial function, as evidenced by reduced microglial activation