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The recommended dose of pemetrexed for injection when administered with cisplatin for initial treatment of locally advanced or metastatic non-squamous NSCLC in patients with a creatinine clearance (calculated by Cockcroft-Gault equation) of 45 mL/min or greater is 500 mg/m 2 as an intravenous infusion over 10 minutes administered prior to cisplatin on Day 1 of each 21-day cycle for up to six cycles in the absence of disease progression or unacceptable toxicity

The hair follicles get progressively smaller over time

Evidence note: PRP has moderate human clinical evidence

Gramer G, Hoffmann GF (2020) Vitamin B12 deficiency in newborns and their mothersnovel approaches to early detection, treatment and prevention of a global health issue