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How to Code Generalized Weakness: Step-by-Step Workflow Step 1: Document onset, duration, and progression The note must state: start date or timeframe worsening, stable, or improving course precipitating events (hospitalization, infection, immobility) Step 2: Record objective strength findings The record must include objective findings, not only patient statements

3.3.1 Mitochondrial fusion and regulatory mechanisms Mitochondrial fusion is a cellular self-repair mechanism that combines healthy mitochondria with damaged or mutated mitochondria to repair the damage or compensate for the mitochondrial dysfunction caused by mutations through complementary effects, thus ensuring normal mitochondrial function and maintaining normal cellular physiological activities (Twig and Shirihai, 2011)

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