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433 Rather than producing from mitochondrial TCA cycle under controlled conditions, the NADH in diabetic islets is generated by cytoplasmic sorbitol oxidation and mitochondrial pyruvate oxidation in response to diabetes and hyperglycemia stimulate

Fahrenholz T, Wolle MM, Kingston HMS, Faber S, Kern JC, Pamuku M, Miller L, Chatragadda H, Kogelnik A (2015) Molecular speciated isotope dilution mass spectrometric methods for accurate, reproducible and direct quantification of reduced, oxidized and total glutathione in biological samples