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The second component tracked the natural history of NAFLD progression in adults, encompassing 14 distinct health states including no steatosis, simple steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, decompensated cirrhosis, hepatocellular carcinoma (HCC), LT, and liver-related or other causes of death

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doi: 10.3390/antiox13091092 187 XieXLinMXiaoGLiuHWangFLiuDet al

Distinct HSC subpopulations and transcriptional programs may play important roles in the transition from advanced fibrosis to cirrhosis in human NASH